Research

Memory consolidation is a complex process that involves many brain areas. The hippocampus plays a central role in forming new memories – it quickly stores new experiences in the form of a cognitive map with its content distributed across the neocortex. Over time, the neocortical representations are consolidated into a stable structures that can be invoked even without participation of the hippocampus.

In our current research, we study the spread of memory reactivations across the neocortical network. Using mathematical methods, we aim at identifying neural ensembles that participate in memory consolidation and, based on their characteristics, separate distinct memory processes.

Recently, our focus shifted towards high-frequency oscillations (80-150Hz) as a bridge between single neuron and population activity that could enable studying memory-related activation patterns across the whole brain.

Using our methods, we investigate how EEG could improve the diagnostic of multiple sclerosis and long-term monitoring of patients.

We actively collaborate with several experimental and clinical research groups:

• Multiple Sclerosis Centre, General University Hospital in Prague, Czechia (Prof. MUDr. Dana Horáková, PhD. , Associate Prof. MUDr. Tomáš Uher, PhD., Jiří Motýl, PhD., MUDr. Barbora Srpová, PhD)
• Prof. Eduardo Fernandez MD, PhD, Miguel Hernández University, Elche, Spain
• Assistant Prof. Dr. rer. Nat. Johanna Senk, University of Sussex, UK

For students

We offer bachelor and master thesis topics ideally suited for students of Bioinformatics, Computer Science or Biology research programmes.

A doctoral study in our group is performed within the Bioinformatics study programme. Students of diverse academic backgrounds are welcome!

If you are interested in a topic that involves analysis of experimental data, contact us by email. We will organize a personal meeting to discuss the possible options.